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Sunday, March 21, 2010   48º F

Updated 07/31/2008 06:30 AM

New, promising Alzheimer drugs being tested

By: Katie Morse

New, promising Alzheimer drugs being tested
SYRACUSE, N.Y. -- Across the U.S., more than five million people are living with Alzheimer's disease. Right now, the medication available only eases the disease symptoms. But a new drug called Rembe, and other new drugs are showing promising results.

"The new group of medications that are coming out are actually more disease-modifying, meaning that they may actually halt the disease process," said Dr. Sharon Brangman, CNY Alzheimer Disease Assistance Center Director.

And Rember could have a huge impact for the estimated 16 million Americans diagnosed by 2015.

"If we can advance that research further so that eventually we have medications that are on the market that are actually suited for modifying the progression of the disease, we will start seeing impact of lowering those numbers," said Cathering James, CNY Alzheimer's Association CEO.

Even though we are hearing a lot about Rember, the drug is still being tested and probably won't be available for a few more years. And that's something that's very difficult for family members and people who are dealing with the disease.

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"There's definitely a frustration. We have family members that hear these news reports and then are calling because they want this medication, as we all do, to be available immediately," said James.

"They are instilling hope in that they may actually modify the disease process. The downside is that it takes several years for them to actually come to market," said Brangham.

Rember is still in clinical tests and physicians say it's not a magic pill, simply another tool to fight this deadly disease.

The Alzheimer's Association says funding is vital to help make new drugs available. Local Memory Walks will help raise money for research. To find a team near you, or for more information, visit the Memory Walk website at alz.org/memorywalk.team.asp

Ten warning signs of Alzheimer’s

Memory loss -- Forgetting recently learned information is one of the most common early signs of dementia. A person begins to forget more often and is unable to recall the information. What’s normal? Forgetting names or appointment occasionally.

Difficulty performing familiar tasks -- People with dementia often find it hard to plan or complete everyday tasks. Individuals may lose track of the steps to prepare a meal, place a telephone call or play a game. What’s normal? Occasionally forgetting why your came into a room or what you planned to say.

Problems with language -- People with Alzheimer’s disease often forget simple words or substitute unusual words, making their speech or writing hard to understand. They may be unable to find their toothbrush, for example, and instead as of “that thing for my mouth.” What’s normal? Sometimes having trouble finding the right word.

Disorientation to time and place -- People with Alzheimer’s disease can become lost in the own neighborhoods, forget where they are and now they got there and not know how to get back home. What’s normal? Forgetting the day of the week or where you were going.

Poor or decreased judgment -- Those with Alzheimer’s may dress inappropriately, wearing several layers on a warm day or little clothing in the cold. They may show poor judgment about money, like giving away large sums to telemarketers. What’s normal? Making a questionable or debatable decision from time to time.

Problems with abstract thinking -- Someone with Alzheimer’s disease may have unusual difficulty performing complex mental tasks, like forgetting what numbers are and how they should be used. What’s normal? Finding it challenging to balance a checkbook.

Misplacing things -- A person with Alzheimer’s disease may put things in unusual places: an iron in the freezer or a wristwatch in the sugar bowl. What’s normal? Misplacing keys or a wallet temporarily.

Changes in mood or behavior -- Someone with Alzheimer’s disease may show rapid mood swings – from calm to tears to anger – for no apparent reason. What’s normal? Occasionally feeling sad or moody.

Changes in personality -- The personalities of people with dementia can change dramatically. They may become extremely confused, suspicious, fearful or dependent on a family member. What’s normal? People’s personalities do change somewhat with age.

Loss of initiative -- A person with Alzheimer’s disease may become very passive, sitting in front of the TV for hours, sleeping more than usual or not wanting to do usual activities. What’s normal? Sometimes feeling weary of work or social obligations.

If you are having many of the 10 warning signs, see a doctor to find the cause. Early diagnosis gives you more opportunity to get treatments and plan for your future. Your local Alzheimer’s Association can help you find the right doctor.